Effect of ethanolic leaf extract of Moringa olifera leaf on haematological and biochemical parameters of wistar rats

Evaluation of the effect of ethanolic leaves extract of Maringa oleifera on Haematological and certain Biochemical parameters was studied. The study assessed Total protein, Albumin, Billirubin for biochemical and PCV, Hb and WBC for haematological indices. Twenty five (25) albino rats of wistar strain (100-175g) were used for the studies and were divided into 5 groups of five (5) rats per each. Group A served as control and was treated with distil water of treatment equivalence, group B, C,D, and E were treated with various concentration the extract as follows; viz: 100mg/kg, 200mg/kg, 300mg/kg, 1g/kg respectively. The administration of the extract lasted for twenty eight (28) days period after which the animals were sacrificed and blood obtained for biochemical and haematological analysis. The result of the study reveals that the ethanolic leaf extract of M. Oleifera lowers seruim bilirubin, but increase albumin, and Total protein levels in all treated groups compared with the controls all at (p<0.05) . More so, similar increased was also recorded for Haemoglobin (Hb) and Hematocrit but no significant (p<0.05) changes was observed for WBC in all treatment groups. The leaves extract of M. oleifera administered orally prove to be biochemically and haematologically save.